Normal blood clotting is necessary for healing wounds. Vitamin K promotes blood clotting and is used to prevent or control internal bleeding and reduce excessive menstrual flow. However, excessive blood clotting is dangerous and can result in coronary thrombosis and thrombophlebitis, the main causes of heart attacks, as well as strokes. The risk of excessive blood clotting is increased by nutrient deficiencies, alcohol and excess arachidonic acid (AA), an essential fatty acid prevalent in meat, dairy products, eggs and peanuts. A vegetarian diet can therefore be beneficial in such cases. A reduction in blood-clotting can be induced by foods such as garlic, onion and oily fish (such as salmon, mackerel and sardines), and the use of supplements such as vitamin E, calcium, evening primrose oil, omega-3 fatty acids (MaxEPA), lecithin, kelp and octacosanol, contained in wheat germ oil.

The coagulation system the third component os the hemostatic process is a major contributor to thrombus formations. The coagulation sequence comprises in essence a series of transformations of proenzymes to activated , culminating in the formation of thrombin which converts the soluble plasma protein fibrinogen to the insoluble fibrous protein fibrin. Protein C and S are two vitamin K., depenedent proteins characterized by their ability to inactivate cofactors Va and VIIIa.These two it will be recalled serve as reaction accelerators in the coagulation cascada. A deficiency of a clotting factor can lead to uncontrolled bleeding. It has two major facets of the clotting mechanism , first is the platelets and second is the thrombin system. It become risky when they block blood flow through an artery or vein. Blood clotting is the process by liquid blood is transformed into a solid state. This blood clotting is a compound procedure linking many clotting factors such as . calcium ions, enzymes, platelets, damaged tissues .The flat muscle in blood vessel ramparts contracts instantly the blood vessel is broken. This response reduces blood loss for some time, while the other haemostatic mechanisms become vigorous.

Prothrombinase is formed in two ways one is central method and it is initiated by fluid blood assembly contact with a foreign surface, i.e. something that is not element of the body and second is Extrinsic method and it is initiated by liquid blood making contact with damaged tissue.The central and the extrinsic method engage connections between coagulation factors. Prothrombinase converts prothrombin, which is a plasma protein that is formed in the liver, into the enzyme thrombin. thrombin converts fibrinogen into fibrin and it is inexplicable and forms the threads that bind the clot.. It may occur for the reason that not enough of the factor is produced and a mutant version of the factor fails to perform